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Addictions are complex disorders, and a combination of preclinical models is used to gain insights into the neurobiological underpinnings

PubMed Central, Korzun, William J

This coordination stabilizes copper in a biologically available form, allowing it to interact with cellular targets without generating oxidative stress. The copper ion also acts as a catalytic cofactor in enzymes involved in collagen cross-linking, antioxidant defense, and wound remodeling

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